Earth vs. the Spider is a 2001 science fiction-horror television film directed by Scott Ziehl. It is the first of a series of films made for Cinemax paying tribute to the films of American International Pictures. The films in this tribute series reused the titles of old American International Pictures films, but are not remakes of the earlier films. The film centers on a shy, obsessive comic book fan who gets injected with an experimental serum derived from spiders, which gives him minor superpowers. As time progresses, more horrific changes occur, slowly transforming him into a grotesque human spider. A detective begins to investigate when bodies start to pile up covered in cobwebs. The film is rated R for violence, nudity, profanity, gore, and profanity. The film was nominated for the Saturn Award at the Academy of Science Fiction, Fantasy, and Horror Films, USA.